Helper T cell differentiation
نویسندگان
چکیده
منابع مشابه
Model Analysis of Helper T Cell Differentiation
Helper T (Th) cells regulate immune responses by producing various cytokines upon antigen stimulation. Helper T cells can be divided into two subsets, Th1 and Th2 [2]. The Th1 cells are responsible for defense against infectious intracellular microorganisms. The Th2 cells are responsible for defense against extracellular pathogens and the development of allergic immune reactions. The SOCS famil...
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Following activation by antigen, helper T cells differentiate into one of many effector phenotypes. Formulating mechanistic mathematical models combining regulatory networks at the transcriptional, translational and epigenetic level, we study how individual helper T cells may adopt their different phenotypes. For each cytokine phenotype, for example, T helper type 1 (Th1) and type 2 (Th2) cells...
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ژورنال
عنوان ژورنال: Cellular & Molecular Immunology
سال: 2019
ISSN: 1672-7681,2042-0226
DOI: 10.1038/s41423-019-0220-6